Eppendorf BioFlo® Bioreactors

You rely on your equipment. Your equipment should rely on ATG.

When your bioreactor requires servicing, downtime isn’t an option—you need precise, efficient intervention. At Analytical Technologies Group, we focus exclusively on the repair and maintenance of systems like the Eppendorf BioFlo® Bioreactor Series, equipping our field service engineers with the expertise to quickly identify and resolve performance issues. Backed by a rigorously managed in-house inventory of critical replacement components, we ensure minimal disruption and a rapid return to full operational capacity for your lab.

Let’s get you up and running – and keep you there.

  • Eppendorf BioFlo® 110

  • Eppendorf BioFlo® 120

  • Eppendorf BioFlo® 320

Tips for keeping your Eppendorf BioFlo® Bioreactor in good working order:

  • Install inline filters on the gas supply lines feeding the controller (especially when using MFCs), and replace them annually.

  • If autoclaving is performed, maintain a log of autoclave cycles for the following:

    • Glass vessels

    • pH probes

    • DO probes

    • Any other probes located within the vessel
      Adhere to the manufacturer’s specified autoclave life cycles and storage recommendations.

  • Replace vessel O-rings annually.

  • When using optical sensors, keep all open connections covered with the supplied protective caps to prevent fouling or contamination of connection points.

  • If the reactor will not be used for an extended period, power it down and, if possible, disconnect it from the power source. These systems rely on high-power electronics that generate significant heat, which can degrade components over time.

  • Have the impeller shaft drive assembly rebuilt annually to prevent component wear and potential contamination of the media.

  • Inspect the rollers in peristaltic pump heads for rolling resistance. They should rotate freely; remove any accumulated residue using a mild detergent to prevent tubing wear.

  • Perform annual preventive maintenance to verify that the system is operating in accordance with manufacturer specifications.

Having technical problems with your Eppendorf BioFlo® Bioreactor?

 

Fast Response

We provide very prompt responses to customers within one business day.

Fast Turnaround

Our field service engineers are expediently dispatched across North America & Europe to fulfill your service request.

Expert Staff

ATG’s highly trained, highly skilled staff ensure your instruments remain in optimal condition.

Parts In Stock

To minimize instrument downtime, we stock virtually all parts for the systems in which we specialize.

 

Eppendorf BioFlo® Bioreactors Troubleshooting Tips:

If pH, DO, or temperature readings look unstable or incorrect:

  • Check calibration status first; Expired calibration is the most common cause.

  • Inspect the membranes of the DO probes, the electrolyte level (if applicable), and optical patches (for fouling or delamination).

  • Confirm that the temperature compensation is functioning and the proper probe polarization time (DO) is achieved.

If acid/base additions overshoot:

  • Check pump calibration (flow rate drift is common), and tubing elasticity (older tubing might lead to a delayed response).

  • Reduce pump speed or pulse duration, and verify probe response time.

If temperature fluctuates:

  • Check the water supply (flow rate and temperature stability), and the heating blanket integrity (for glass vessels)

  • Inspect RTD / temperature probe seating

  • Eliminate ambient drafts or HVAC effects

ATG: YOUR PARTNER IN BIOPROCESS SERVICE, SUPPORT and MAINTENANCE