Applikon® Bioreactors
You rely on your equipment. Your equipment should rely on ATG.
If your bioreactor needs service, you need the work done quickly and correctly. Since Analytical Technologies Group specializes in the repair and maintenance of bioreactors, such as the Applikon® ez-control, ez2-control, and my-control, our field service engineers have the necessary knowledge to rapidly diagnose and remedy any issues you may be experiencing. Our diligently maintained in-house inventory of replacement parts allows us to provide the rapid service you need to get your lab back to full productivity.
Let’s get you up and running – and keep you there.
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Applikon® my-Control
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Applikon® ez2-Control
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Applikon® ez-Control
Tips for keeping your Applikon® Bioreactors in good working order:
To clean auxillaries and tubing:
Disassemble the bioreactor system and remove all tubing and auxiliaries that are inserted in the reactor (side wall and head plate). These assemblies must be cleaned “off-place” with the same cleaning solutions as were used for thereactor.
Rinse thoroughly with tap water (3 times).
Rinse with de-ionized water (or Water For Injection / High Purity Water).
Check the quality of O-rings and gaskets during reassembling. Replace them if necessary.
When using optical sensors, keep all open connections covered with the supplied protective caps to prevent fouling or contamination of connection points.
If the reactor will not be used for an extended period, power it down and, if possible, disconnect it from the power source. These systems rely on high-power electronics that generate significant heat, which can degrade components over time.
Have the impeller shaft drive assembly rebuilt annually to prevent component wear and potential contamination of the media.
Inspect the rollers in peristaltic pump heads for rolling resistance. They should rotate freely; remove any accumulated residue using a mild detergent to prevent tubing wear.
Perform annual preventive maintenance to verify that the system is operating in accordance with manufacturer specifications.
Having technical problems with your Applikon® Bioreactors?
Fast Response
We provide very prompt responses to customers within one business day.
Fast Turnaround
Our field service engineers are expediently dispatched across North America & Europe to fulfill your service request.
Expert Staff
ATG’s highly trained, highly skilled staff ensure your instruments remain in optimal condition.
Parts In Stock
To minimize instrument downtime, we stock virtually all parts for the systems in which we specialize.
Applikon® Bioreactors Troubleshooting Tips:
Verify Sensor Calibration and Signal Integrity:
Before interpreting unexpected process values, confirm that all sensors—particularly pH, dissolved oxygen, and temperature probes—are correctly calibrated and providing stable signals. Drift, electrical noise, or poor electrode maintenance can often exhibit process deviations.
Inspect Control Loops for Proper Tuning:
If the system exhibits oscillations or fails to reach setpoints efficiently, review PID tuning parameters for each control loop. Overly aggressive or sluggish control behavior often points to improper tuning rather than mechanical failure.
Confirm Gas Flow and Mixing Uniformity:
Irregular DO or pH readings may result from inadequate gas sparging or mixing inefficiency. Check for clogged spargers, leaks in gas lines, or improper impeller speed settings to ensure homogeneous mixing as well as mass transfer.
Assess Software Configuration and Communication Links:
Unexpected control responses or data loss may stem from software misconfigurations or communication errors between the controller and peripheral devices. Verify firmware versions, communication protocols, and ensure that all device addresses are correctly assigned.
Evaluate Sterility and Mechanical Integrity Before Each Run:
Inconsistent culture performance often originates from undetected leaks or contamination. Inspect vessel seals, sampling ports, and tubing connections for wear or residue.
